LEADERS IN RESEARCH, DEVELOPMENT AND INNOVATION

BIOCONTROL AND BIOSTIMULANT RESEARCH

45% of the company's staff is made up of research staff.

Research, development and innovation (R&D+I)

Since Futureco Bioscience was founded in 1993, the R&D&I Department has been researching and developing products based on natural extracts and microbial agents with biostimulant or biopesticide activity.

The R&D department has a high screening capacity to select biostimulant microorganisms for plant biological functions, or microorganisms with biopesticidal activity (CBAs) for the control of fungi (biofungicides), bacteria (biobactericides), insects (bioinsecticides) or pathogenic nematodes (bionematicides), both in vitro, ex vivo and in vivo.

More than 1,500 in vitro bioassays and 200 ex vivo bioassays are conducted annually, selecting the most effective and innovative active ingredients and CBAs. In addition, around 300 in vivo (in-plant) bioassays are carried out annually in climatic chamber or greenhouse conditions, where both the selected active ingredients and their formulations are evaluated and validated. This capability makes Futureco Bioscience one of the most active companies worldwide in the development of biostimulants and biopesticides.

Today, as a result of investment in R&D+I, 45% of the company’s staff is made up of research staff.

The department's main lines of research are:

MICRO-ORGANISMS

Futureco Bioscience has its own collection of more than 3000 fungi and bacteria. After their identification and molecular characterisation, their efficacy as biocontrol agents on different targets (pests, nematodes, fungi and phytopathogenic bacteria) or their biostimulant action (anti-salt/hydric stress, phytoremediation, “rebalancing” of biogeochemical cycles (N, P, C…), and rooting, among others) is evaluated.

MICROBIAL METABOLITES

Identification of organic compounds of microbial origin (protein compounds and peptides), with potential activity in pathogen control or as biostimulants. The aim is to identify micro-organisms producing bioactive compounds of interest in order to add value to new formulations.

MICROBIAL METABOLITES

Of particular interest are those with an antimicrobial or insecticidal effect. Extracts are selected from the best quality sources and, after formulation, evaluated against different targets using a proprietary standardised system.

SEAWEED

Formulations based on multicellular brown algae (Phaeophyceae) of the order Fucales (Ascophyllum nudosum) and Laminariales (Laminaria digita, Eklonia maxima), or unicellular cyanobacteria grouped in colonies (Spirulina pratensis) with the aim of developing new formulations that allow the crop to overcome different abiotic stresses.

PEPTIDES

Antimicrobial peptides produced by fungi described in the literature or worked from the microorganisms included in the Futureco Bioscience Collection. Prototypes based on peptides with nematicidal activity selected from by-products of the agri-food industry are also being evaluated.

RNAi

RNA interference (RNAi)-based biopesticides: a defence system of eukaryotic organisms against exogenous RNA. This technology can be used to knock down the expression of any gene of interest. Thus, an RNAi-based biopesticide can inactivate specific genes of the pathogen or any target organism.

R&D+I projects

Between 1999 (date of foundation of the R&D+I Department) and 2018, the main projects developed or in progress are:

1999-2009

NOFLY

Our team is constantly researching and applying cutting-edge technologies and methodologies that allow us to differentiate ourselves and fully meet the demands of the sector. We maintain an open and creative attitude, at all levels of the organisation, to incorporate technological and environmental advances.

2005-2007

NOPIC

CDTI project: Development of a bioinsecticide based on the fungus Metarrhizium anisopliae strain TF251 for the control of the black banana weevil. Five were sampled from the Canary Islands and 48 strains of Metarrhizium were isolated. The selected strain (TF251) was characterised and a formulated prototype (WP) was designed. Its efficacy was evaluated under laboratory, semi-field and field conditions. Strain TF251 is available for further development.

2007-2009

NONEM

CIDEM project: Preliminary development of a new nematicide for the biological control of phytonematodes based on a bacterial strain (confidential). This research project laid the groundwork for the development of future bionematicides also formulated from bacteria (and which have led to the bionematicides currently available in the pipeline strains B410, B25 and B24).

2012-2014

MICROSAFE

CDTI project: Preliminary development of a biofungicide and bactericide for the control of Rhizoctonia and Sclerotinia fungi and Erwinia bacteria in potato, lettuce and tomato crops, respectively. Bacteria B2017 (Pseudomonas putida) and B2021 (P. azotoformans) were isolated during this project. In the year 2014-2021, the required studies for its registration as a biofungicide-biobactericide including other fungi and bacteria of commercial interest have been carried out.

2016-2018

ENZYTECH

CIDEM Project. Development of Enzymatic Technologies (of microbial origin) from plant by-products from the agri-food industry to obtain bioactive molecules with low-risk biostimulant and/or phytosanitary action. Different protein hydrolysates with high nematicidal activity (Meloidogyne) were identified in cucumber and tomato crops.

2018-2021

INNOLIVAR

Licitation UCO and Ministry of Economy, Industry and Competitiveness (FEDER Funds). Development of a bioinsecticide based on the entomopathogenic fungus Metarhizium brunneum strain EAMb 09/01-Su (isolated by the Applied Entomology group of the University of Cordoba) for the control of the olive fruit fly. The project consisted of strain characterisation, design of formulated prototypes, field evaluation and soil persistence studies using molecular markers.

2018-2022

PALVIP

INTERREG-POCTEFA project (FEDER funds). Collaborative project in which Futureco Bioscience participated producing 2 microbial biofungicides (B2017 and B2021) and a botanical extract (BESTCURE) which were evaluated for the control of downy mildew, powdery mildew and Botrytis in grapevine and Moniliosis in stone fruit trees under field conditions (in Spain and France).

2018-2023

FUTUROMICS

Internal project. Evaluation of the effect of different commercial (e.g. Bioradicant, Radisan, Fitomaat, Hydromaat, Cromaliv, Ultra V, among others) and experimental (B2017OD, B25OD, B24OD etc) products on different crops using molecular transcriptomics techniques that allow simultaneous evaluation of the expression levels of multiple genes in a given tissue at a specific time.

Forthcoming launches

Partner organisations

Ecoletters

Publications that demonstrate the efficacy, quality and safety of Futureco Bioscience products.

Citogrower 2% increases the size, number and weight of fruits on avocado crops

7 November 2023

Hectares treated with CITOGROWER® 2% averaged 2210 kg/ha while those treated with control averaged 1922.5 kg/ha. That is, CITOGROWER® 2% achieved a difference of 287.5 kg/ha: 13% increase in production per hectare.

LEADERS IN RESEARCH, DEVELOPMENT AND INNOVATION

Research, development and innovation (R&D+I)

The department's main lines of research are:

MICRO-ORGANISMS

MICROBIAL METABOLITES

MICROBIAL METABOLITES

SEAWEED

PEPTIDES

RNAi

R&D+I projects

NOFLY

NOPIC

NONEM

MICROSAFE

ENZYTECH

INNOLIVAR

PALVIP

FUTUROMICS

Forthcoming launches

Partner organisations

Ecoletters

Citogrower 2% increases the size, number and weight of fruits on avocado crops

How to improve cucumber curdling and rice fattening with Ecormon

Bioradicante not only increases root germination and length

Yield increase in Criolla potato crop (Solanum phureja) with Botamisol 45

NOFLY exceeds the biological standard efficacy and proves its relevance in the reduction of chemical treatments

Biological insecticide NOFLY is effective against whitefly in soybean

Bestcure controls “acid rot” acetobacter aceto in grapevine

CITOGROWER AND CITOFOUR remain stable for at least four years

HYDROMAAT REDUCES DROUGHT STRESS IMPACT ON TOMATO PLANTS

Efficacy of BESTCURE® against bacterial spot and early blight on tomatoes

Articles

No antibiotic and toxic metabolites produced by the biocontrol agent Pseudomonas putida strain B2017

Design of Bacterial Strain-Specific qPCR Assays Using NGS Data and Publicly Available Resources and Its Application to Track Biocontrol Strains

Diseño y evaluación de prototipos bioinsecticidas para el control de la mosca del olivo

Pseudomonas putida strain B2017 produced as technical grade active ingredient controls fungal and bacterial crop diseases

Draft Genome Sequence and Assembly of a Lysobacter enzymogenes Strain with Biological Control Activity against Root Knot Nematodes

Control of blue mould and bitter rot of apples, and brown rot of peaches by Citrus aurantium extractbased product BIOLASTING®

Natural occurrence of fungal egg parasites of root-knot nematodes, Meloidogyne spp. in organic and integrated vegetable production systems in Spain

Evaluación in vitro de la capacidad antagonista de Trichoderma lignorum FEEP TL0601 frente a Fusarium oxysporum f.sp. lycopersici