Spore-based bioinsecticide made with Cordyceps fumosorosea (Isaria fumosorosea, Paecilomyces fumosoroseus) that controls whiteflies, thrips, aphids and mites at any stage of their life cycle.


NOFLY is a very effective biological insecticide active against all life cycle stages of different species of whiteflies (Bemisia, Trialeurodes, Lecanoideus, Aleuroidicus). Moreover, NOFLY has insecticidal action against aphids, thrips, some caterpillars, and also other insects that often cause significant economic losses to farmers.

  1. Field of activity: Control of whiteflies (Bemisia tabaci, Trialeurodes vaporariorum, Bemisia argentifolii, Lecanoideus floccissimus) in all stages (eggs, larvae and adults).
  2. Recommended use: Good growth in a temperature range between 8 and 30 °C, with optimum growth between 20 and 30 °C. The highest development of the fungus has been observed at 25 °C, with high relative humidity and low intensity of solar radiation. It is therefore recommended to apply in the early morning or late afternoon. Do not apply at temperatures above 30 °C.
  3. Visible effects on the pest before death: for example clear loss of coordination and loss of movement, while stop feeding and color change to red/pink
  4. Monitoring and comparing with initial population: Yellow sticky traps, visual perception of the pest level, weekly counts


Cordyceps fumosorosea FE 9901 2x10E9 spores* (*Inert 82%).

Active ingredient: Cordyceps fumosorosea

  • Strain: FE 9901
  • Concentration: 2.0×109 spores/g
  • Type: Wettable powder
  • Moisture content: < 5% w/w
  • pH (1% dilution): 6.0 – 7.0
  • Density: 0.7 g/cc
  • Storage: ~ 18 months at 4ºC, 6-12 months at RT (25ºC)

*C. fumosorosea is not a plant pathogenic organism and does not produce significant detrimental effects on beneficial insects, including bees and bumblebees.



0,2 Kg

0,5 Kg

1 Kg




Action mode:

NOFLY is a contact biological insecticide

Like most entomopathogenic fungal species, the infection cycle of NOFLY is as follows: spore attachment, germination, penetration, vegetative growth and conidiogenesis. Firstly, Paecilomyces fumosoroseus spores attach to the cuticle of the insect in either immature stages (eggs or larvae) or on adults by hydrophobic interactions between the spore wall and the lipid layer of the epicuticle. Under favourable conditions, the spore is able to germinateand penetrate the body of the insect through the waxes, chitins and proteins of the cuticle; consequently the insect stops feeding and reproducing (10h) and the fungus reaches the haemocoel within 24 hours.  In conclusion, within the insect, multiplication of the fungus takes place by the formation of new hyphal bodies within 48 hours. Lastly, under conditions of high humidity, the fungus grows externally on the individual, producing new spores (dissemination) within 72 hours of the onset of infection. Sporulation reaches its maximum after 5-7 days.

Mode of action of NOFLY during infection

  1. Attachment
  2. At contact, the spores attach to the insect’s cuticle through hydrophobic interaction between the spore’s wall and the lipid layer of the epicuticle.
  3. Germination
  4. The spores germinate on the insect and the hyphae penetrate the wax, chitin and protein matrices of the cuticle. The insect stops feeding or reproducing.
  5. Growth
  6. C. fumosorosea begins to multiply within the host cuticle and forms new hyphae. The enzymes released cause muscle paralysis and eventually death.
  7. Sporulation
  8. The fungus grows and, in high relative moisture conditions, emerge from the insect’s body, producing new infective spores.

Benefits and advantages

  1. Without residues nor re-entry interval (rei)
  2. Compatible with other insecticides & fungicides
  3. Certified for organic agriculture
  4. No toxicity for pollinators
  5. This fungus is capable of infecting any of the insect stages: egg, larva and adult, although the most sensitive stage is the N1 larva stage.

User and storage recommendations

  • Start the treatment at the first symptoms of pest. It is recommended monitoring pest population for example through yellow sticky traps, or visual perception of the pest level and weekly countings.
  • Make at least 3 applications every 3-7 days (maximum 10 days).
  • NOFLY must come into contact with the insect, reaching both sides of the leaves. Soil application is recommended to break the life cycle of insects which happens on the soil (for example thrips on pupal stage).
  • NOFLY can be applied at any time during the crop cycle, even during the harvest period (no PHI).
  • The spores of Cordyceps fumosorosea are susceptible to high temperatures, dryness and UV radiation. A high relative moisture favours its mode of action, therefore a previous irrigation might be recommendable.
  • NOFLY is stable for at least 1 year if kept under refrigeration conditions. At room temperature, it is stable during 6 months. Keep in a fresh and ventilated place with temperatures below 26ºC. Do not store for long periods under direct sunlight.
  • NOFLY is compatible with other biological control practices and pesticide products, it does not leave residues, and does not have any re-entry intervals (REI).

NOFLY registrations

NOFLY is already authorized for use in organic farming in accordance with EU, NOP and JAS standards by internationally recognized certifiers such as OMRI and BCS. Currently NOFLY is registered and commercialized in Austria, Belgium, Canada, Chile, Colombia, Cyprus, Ivory Coast, Ecuador, Spain, France, Greece, Guatemala, Netherlands, Honduras, Hungary, Italy, Kenya, Morocco, Mexico, Peru, Poland, Dominican Republic, Romania, UK and USA. Notably, in USA, the EPA (Environmental Protection Agency) has approved the use of NOFLY in outdoor and residential crops. Finally, NOFLY is registered for use on multiple crops including the main horticultural, aromatic, herbaceous ornamentals, and leguminous crops.



Demonstration trials

Futureco Bioscience
Av. del Cadí, 19-23 P.l.
Sant Pere Molanta 08799
Olèrdola, Barcelona España (ES)



Organic biofungicide and biobactericide that activates the natural defences of plants.