NOFLY bioinsecticida


Bioinsecticide based on spores of Paecilomyces fumosoroseus (Isaria fumosorosea, Cordyceps fumosorosea) for the control of whitefly, thrips and other pests.

NOFLY also has insecticidal action against aphids, thrips, some caterpillars, and other insects that often cause significant economic losses to farmers.


  • Active ingredient: 18 % Paecylomyces fumosoroseus
  • Strain: FE 9901
  • Concentration: 2.0×109 spores/g
  • Type: Wettable powder
  • Moisture content: < 5% w/w
  • pH (1% dilution): 6.0 – 7.0
  • Density: 0.7 g/cc
  • Storage: ~ 18 months at 4ºC, 6-12 months at RT (25ºC)


Cordyceps fumosorosea FE9901 (18,0 %w/w)

Inerts (82,0 %w/w)

*C. fumosorosea is not a plant pathogenic organism and does not produce significant detrimental effects on beneficial insects, including bees and bumblebees.



0,2 Kg

0,5 Kg

1 Kg




Action mode:

Whats is NOFLY wp?

Based on spores of the proprietary strain FE9901 from Cordyceps fumosorosea (before named Isaria fumosorosea and Paecilomyces fumosoroseus), an entomopathogenic fungus natural enemy of several insect pests, NOFLY has been proven to be a very effective bioinsecticide, active against all life cycle stages of different species of whiteflies (Bemisia, Trialeurodes, Lecanoideus, Aleuroidicus)

NoFly Bioinsecticide for the control of whitefly and other pests. A pathogenic fungus belonging to the Deuteromycotin family, intended for whitefly control. The formulated product contains 18% w/w of blastospores at a concentration of 2×109 CFU/g. The mode of action is contact initiated. This fungus is capable of infecting any of the insect stages: egg, larva and adult, although the most sensitive stage is the N1 larva stage. Like most entomopathogenic fungal species, the infection cycle is as follows: spore attachment, germination, penetration, vegetative growth and conidiogenesis.

Paecilomyces fumosoroseus spores attach to the cuticle or dorsum of the insect in either immature stages (eggs or larvae) or on whitefly adults by hydrophobic interactions between the spore wall and the lipid layer of the epicuticle. Under favourable conditions, the spore is able to germinate, generate a hyphae and penetrate the body of the insect through the waxes, chitins and proteins of the cuticle.

Spore-based bioinsecticide for the control of whiteflies thrips and other pests

The insect stops feeding and reproducing (10h) and the fungus reaches the haemocoel within 24 hours. Within the insect, multiplication of the fungus takes place by the formation of new hyphal bodies within 48 hours. Under conditions of high humidity, the fungus grows externally on the individual, producing new spores (dissemination) within 72 hours of the onset of infection. Sporulation reaches its maximum after 5-7 days.
The microbiological entity Paecilomyces fumosoroseus strain FE 9901 does not produce toxins that are related to its mode of action on susceptible insects.

  1. Field of activity: Control of whiteflies (Bemisia tabaci, Trialeurodes vaporariorum, Bemisia argentifolii, Lecanoideus floccissimus) in all stages (eggs, larvae and adults).
  2. Recommended use: Good growth in a temperature range between 8 and 30 °C, with optimum growth between 20 and 30 °C. The highest development of the fungus has been observed at 25 °C, with high relative humidity and low intensity of solar radiation. It is therefore recommended to apply in the early morning or late afternoon. Do not apply at temperatures above 30 °C.
  3. Visible effects on the pest before death: Loss of coordination and loss of movement, stop feeding, color change to red/pink
  4. Monitoring and comparing with initial population: Yellow sticky traps, visual perception of the pest level, weekly counts

NO FLY wp registrations

NOFLY is authorized for use in organic farming in accordance with EU, NOP and JAS standards by internationally recognized certifiers such as OMRI and BCS. Currently NOFLY is registered and commercialized in Austria, Belgium, Canada, Chile, Colombia, Cyprus, Ivory Coast, Ecuador, Spain, France, Greece, Guatemala, Netherlands, Honduras, Hungary, Italy, Kenya, Morocco, Mexico, Peru, Poland, Dominican Republic, Romania, UK and USA. Notably, in USA, the EPA (Environmental Protection Agency) has approved the use of NOFLY in outdoor and residential crops. NOFLY is registered for use on multiple crops including the main horticultural, aromatic, herbaceous ornamentals, and leguminous crops.

Nofly is a contact bioinsecticide

1. Attachment

At contact, the spores attach to the insect’s cuticle through hydrophobic interaction between the spore’s wall and the lipid layer of the epicuticle.

2. Germination

The spores germinate on the insect and the hyphae penetrate the wax, chitin and protein matrices of the cuticle. The insect stops feeding or reproducing.

3. Growth

C. fumosorosea begins to multiply within the host cuticle and forms new hyphae. The enzymes released cause muscle paralysis and eventually death.

4. Sporulation

The fungus grows and, in high relative moisture conditions, emerge from the insect’s body, producing new infective spores.

Benefits and advantages

  1. Without residues nor re-entry interval (rei)
  2. Compatible with other insecticides & fungicides
  3. Certified for organic agriculture
  4. No toxicity for pollinators

Nofly user recommendations

  • Start the treatment at the first symptoms of pest. It is recommended monitoring pest population through yellow sticky traps, visual perception of the pest level and weekly countings.
  • Make at least 3 applications every 3-7 days (maximum 10 days).
  • NOFLY wp is a contact insecticide, the product must come into contact with the insect, reaching both sides of the leaves, creating an optimal fog. Soil application is recommended to break the life cycle of insects which happens on the soil (i.e. Thrips on pupal stage).
  • NOFLY wp can be applied at any time during the crop cycle, even during the harvest period (no PHI).
  • The spores of Cordyceps fumosorosea are susceptible to high temperatures, dryness and UV radiation, thus, applications must be done avoiding unfavourable conditions. A high relative moisture favours its mode of action, therefore a previous irrigation might be recommendable.
  • NOFLY wp is stable for at least 1 year if kept under refrigeration conditions. At room temperature, it is stable during 6 months. Keep in a fresh and ventilated place with temperatures below 26ºC. Do not store for long periods under direct sunlight.
  • NOFLY wp is compatible with other biological control practices and pesticide products, it does not leave residues, and does not have any re-entry intervals (REI).
  • For mixing with any other product, before application, it is necessary to conduct a compatibility test, in small volume.


Demonstration trials

Futureco Bioscience
Av. del Cadí, 19-23 P.l.
Sant Pere Molanta 08799
Olèrdola, Barcelona España (ES)



Organic biofungicide and biobactericide formulated based on biocidal extracts and activators of natural plant defences